Sildenafil can be a powerful and selective inhibitor of cGMP-specific phosphodiesterase kind five (PDE5), which is liable for degradation of cGMP in the corpus cavernosum. The molecular framework of sildenafil is comparable to that of cGMP and functions to be a aggressive binding agent of PDE5 within the corpus cavernosum, resulting in more cGMP and enhanced penile response to sexual stimulation.
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Your health practitioner may start you over a reduced dosage of sildenafil. This can aid protect against levels of this drug from building up in your body.
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Alpha-blockers are occasionally prescribed for prostate difficulties or high hypertension. In a few individuals, using VIAGRA with alpha-blockers may result in a drop in hypertension or to fainting
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If you believe you’ve taken excessive of this drug, connect with your health practitioner or community poison Regulate Middle. If your signs or symptoms are extreme, contact 911 or drop by the nearest crisis place immediately.
VIAGRA has sildenafil, which is similar medication present in An additional drug known as REVATIO. REVATIO is utilized to treat a scarce sickness termed pulmonary arterial hypertension (PAH).
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The commonest side effects of VIAGRA: headache; flushing; upset belly; irregular eyesight, such as adjustments in shade eyesight (which include getting a blue coloration tinge) and blurred vision; stuffy or runny nose; back again agony; muscle discomfort; nausea; dizziness; rash.